Hypobaric Hypoxia: Effects on Early Development of Tryptophan Oxygenase in Neonatal Rats
- 12 December 1969
- journal article
- other
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 166 (3911), 1412-1413
- https://doi.org/10.1126/science.166.3911.1412
Abstract
Despite a reduction in liver and body weights of neonatal rats born and reared at a simulated altitude of 5790 meters (oxygen pressure, 76.36 millimeters of mercury), the hepatic enzyme tryptophan oxygenase develops prematurely in these stressed animals as compared to controls reared at sea level. Also, the specific activities remain distinctly elevated through the first 9 days of age; thus, the competence for premature synthesis ot tryptophan oxygenase is confirmed in neonatal rats.Keywords
This publication has 12 references indexed in Scilit:
- Enzymic Differentiation in Mammalian LiverScience, 1969
- Influence of hypoxia, glucocorticoid, and endotoxin on hepatic enzyme inductionAmerican Journal of Physiology-Legacy Content, 1968
- Circadian Oscillation in Rat Liver Tryptophan Pyrrolase and its Analysis by Substrate and Hormone InductionNature, 1968
- Factors affecting the premature induction of tyrosine aminotransferase in foetal rat liverBiochemical Journal, 1968
- Effect of hypophysectomy and growth hormone on the inductions of rat liver tyrosine aminotransferase and tryptophan oxygenase by hydrocortisoneArchives of Biochemistry and Biophysics, 1968
- Effect of Feeding L-Tyrosine to Pregnant Rabbits on the Tyrosine Oxidising Activity of Their OffspringNeonatology, 1968
- Regulation of development of hepatic glucokinase in the neonatal rat by the dietBiochemical Journal, 1967
- The Effect of Development and Hydrocortisone on Tryptophan Oxygenase, Formamidase, and Tyrosine Aminotransferase in the Livers of Young Rats*Biochemistry, 1967
- Age-Dependent Changes of MetabolismNeonatology, 1967
- Circadian Rhythm for Tryptophan Pyrrolase Activity and Its Circulating SubstrateScience, 1966