An orbital meningo-encephalocele with microphthalmia is a very rare condition. Few reports appear in the literature, and for this reason, and also because of the difficulty in its diagnosis and surgical treatment, this case is presented. REPORT OF CASE An Italian girl, aged 6½ years, was admitted to the Manhattan Eye, Ear and Throat Hospital, Oct. 15, 1926. The child's parents were 30 and 40 years of age, respectively, and had always been in excellent health. They had two other children, one younger and one older, both in normal condition, and not showing any congenital anomalies. The mother stated that this child was born with the existing eye condition. The patient was well nourished and bright, and did not evince mental symptoms. No congenital anomalies existed except those present in both eyes. The teeth were in bad condition, enlarged cervical glands were palpable on the left side, and a slight