Further Purification of the Follicle-Stimulating Hormone and Its Effect in Normal and Hypophysectomized Rats.
- 1 January 1946
- journal article
- research article
- Published by Frontiers Media SA in Experimental Biology and Medicine
- Vol. 61 (1), 57-61
- https://doi.org/10.3181/00379727-61-15225
Abstract
A method is described for the prepn. of follicle-stimulating prepns. by tryptic digestion and the removal of a fraction which caused reactions in the human being at the site of injn. Prepns. made by the tryptic digestion method before and after it was changed to remove the local reacting factor were assayed both in normal and hypophysectomized rats. By macroscopic observation the ovaries from both kinds of rats appeared to contain only follicles but microscopic examination showed that a few ovaries contained small amts. of lutein tissue.Keywords
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