Phosphoenolpyruvate Carboxykinase Overexpression Selectively Attenuates Insulin Signaling and Hepatic Insulin Sensitivity in Transgenic Mice
Open Access
- 1 June 2002
- journal article
- Published by Elsevier in Journal of Biological Chemistry
- Vol. 277 (26), 23301-23307
- https://doi.org/10.1074/jbc.m200964200
Abstract
No abstract availableKeywords
This publication has 48 references indexed in Scilit:
- Effects of Free Fatty Acids on Gluconeogenesis and Autoregulation of Glucose Production in Type 2 DiabetesDiabetes, 2001
- Nuclear Magnetic Resonance Studies of Hepatic Glucose Metabolism in HumansRecent Progress in Hormone Research, 2001
- Phosphoenolpyruvate Carboxykinase Is Necessary for the Integration of Hepatic Energy MetabolismMolecular and Cellular Biology, 2000
- Effects of Increased Glucokinase Gene Copy Number on Glucose Homeostasis and Hepatic Glucose MetabolismJournal of Biological Chemistry, 1997
- Fatty Acids Mediate the Acute Extrahepatic Effects of Insulin on Hepatic Glucose Production in HumansDiabetes, 1997
- REGULATION OF PHOSPHOENOLPYRUVATE CARBOXYKINASE (GTP) GENE EXPRESSIONAnnual Review of Biochemistry, 1997
- Causal linkage between insulin suppression of lipolysis and suppression of liver glucose output in dogs.Journal of Clinical Investigation, 1996
- Free Fatty Acid as a Link in the Regulation of Hepatic Glucose Output by Peripheral InsulinDiabetes, 1995
- Vanadate normalizes hyperglycemia and phosphoenolpyruvate carboxykinase mRNA levels in
ob ob Metabolism, 1994 - Transgenic mice overexpressing phosphoenolpyruvate carboxykinase develop non-insulin-dependent diabetes mellitus.Proceedings of the National Academy of Sciences, 1994