THE BIOLOGICAL ASSAY OF FRACTIONS OF GONADOTROPHIN FROM HUMAN PITUITARY GLANDS

Abstract

SUMMARY: Four gonadotrophic fractions from human pituitary glands have been assayed in terms of the International Reference Preparation, HMG 24, by four different methods. These are the assay for total gonadotrophin which depends on the increase in uterine weight of the immature mouse, the augmentation method for follicle-stimulating hormone, the increase in weight of the ventral prostate of the hypophysectomized rat for interstitial cell-stimulating hormone and the ovulation method for the 'ovulating ' factor. The results have been contrasted and discussed.