Effects of Purified Human Interleukin-1 on the Release of Prostaglandin E2 from Fibroblasts

Abstract

Catabolin has been injected into the cerebral ventricles of conscious rabbits It caused a dose-related fever in the low nanogram range. The fever was totally suppressed by preincubation with a catabolin antiserum. The results strengthen the similarity between catabolin and interleukin-1