Conjugated Addition to 2,2-Dimethyl-3(2h)-furanone: Support for the Baldwin Rules for Ring Closure

Abstract
In connection with our exploratory studies directed at devising a total synthetic approach to jatro-phone1 and related antitumor agents,2 we have recently explored conjugate addition of organocuprates3 to the 3 (2H)-furanone ring system. In this letter we document the results of that study.

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