Recurrence of positive SARS‐CoV‐2 in patients recovered from COVID‐19
- 25 May 2020
- journal article
- letter
- Published by Wiley in Journal of Medical Virology
- Vol. 92 (11), 2366-2367
- https://doi.org/10.1002/jmv.26056
Abstract
Recurrence of positive SARS CoV‐2 PCR has been described in patients discharged from hospital after 2 consecutive negative PCR. We discuss possible explanations including false negative, reactivation and re‐infection and propose different strategy to solve this issue. Prolonged SARS‐CoV‐2 RNA shedding and recurrence of viral RNA shedding in asymptomatic patients remain unknown. Transmission of SARS‐CoV‐2 by asymptomatic carriers had been documented. Considering the significance of this ongoing global public health emergency, it is necessary to carry out large studies to better understand the issue of potential SARS‐CoV‐2 recurrence in COVID‐19 patients.Keywords
This publication has 10 references indexed in Scilit:
- False negative of RT‐PCR and prolonged nucleic acid conversion in COVID‐19: Rather than recurrenceJournal of Medical Virology, 2020
- Serological tests facilitate identification of asymptomatic SARS‐CoV‐2 infection in Wuhan, ChinaJournal of Medical Virology, 2020
- Asymptomatic SARS‐CoV‐2 infected case with viral detection positive in stool but negative in nasopharyngeal samples lasts for 42 daysJournal of Medical Virology, 2020
- Asymptomatic cases with SARS‐CoV‐2 infectionJournal of Medical Virology, 2020
- Prolonged SARS‐CoV‐2 RNA shedding: Not a rare phenomenonJournal of Medical Virology, 2020
- False negative rate of COVID-19 is eliminated by using nasal swab testTravel Medicine and Infectious Disease, 2020
- Polymerase Chain Reaction Assays Reverted to Positive in 25 Discharged Patients With COVID-19Clinical Infectious Diseases, 2020
- Stability issues of RT‐PCR testing of SARS‐CoV‐2 for hospitalized patients clinically diagnosed with COVID‐19Journal of Medical Virology, 2020
- Clinical characteristics of severe acute respiratory syndrome coronavirus 2 reactivationJournal of Infection, 2020
- Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort studyThe Lancet, 2020