ULTRAVIOLET IRRADIATION OF PYRIMIDINE DERIVATIVES: III. INFLUENCE OF HYDROGEN CYANIDE ON THE PHOTOLYSIS
- 1 August 1959
- journal article
- research article
- Published by Canadian Science Publishing in Canadian Journal of Chemistry
- Vol. 37 (8), 1281-1287
- https://doi.org/10.1139/v59-191
Abstract
The presence of HCN in concentrations up to 0.05 M in aqueous, buffered solutions of uracil, uridine, and 1,3-dimethyluracil has been shown to divert the normal course of the photochemical hydration reactions of these compounds as a result of photochemically induced combination between HCN and the pyrimidine derivative. A simple calculation indicates that HCN is more efficient than water in reacting with activated uracil molecules by a factor of about 103. The possible general significance of such nucleophilic addition reactions in the photochemistry of nucleic acids is discussed.This publication has 3 references indexed in Scilit:
- Photochemistry of Nucleic Acids and Related Compounds. I. The First Step in the Ultraviolet Irradiation of 1,3-Dimethyluracil1,2Journal of the American Chemical Society, 1958
- The Photochemistry of Uridylic AcidRadiation Research, 1954
- Chromatographic studies of nucleic acids. 1. A technique for the identification and estimation of purine and pyrimidine bases, nucleosides and related substancesBiochemical Journal, 1949