Facilitated calcium diffusion by intestinal calcium-binding protein
- 1 March 1983
- journal article
- research article
- Published by American Physiological Society in American Journal of Physiology-Cell Physiology
- Vol. 244 (3), C303-C307
- https://doi.org/10.1152/ajpcell.1983.244.3.c303
Abstract
The calcium flux through an aqueous compartment was determined using a flow-through dialysis cell in which two dialysis membranes isolated the aqueous compartment. Addition of the intestinal vitamin D-dependent calcium-binding protein (CaBP) significantly enhanced the calcium flux at near physiological calcium concentrations (1 X 10(-6) M). Bovine serum albumin had no effect on the calcium flux. CaBP appears to be one of a class of low molecular weight, soluble binding proteins that enhance ligand diffusion.Keywords
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