Intrathecal Capsaicin Depletes Substance P in the Rat Spinal Cord and Produces Prolonged Thermal Analgesia
- 26 October 1979
- journal article
- other
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 206 (4417), 481-483
- https://doi.org/10.1126/science.228392
Abstract
A single intrathecal injection of capsaicin depletes substance P from primary sensory neurons and causes a prolonged increase in the thermal and chemical pain thresholds of the rat but no apparent change in responses to noxious mechanical stimuli.Keywords
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