The Molecular Ratios of Soluble Rabbit Antigen-Antibody Complexes
- 1 September 1957
- journal article
- research article
- Published by The American Association of Immunologists in The Journal of Immunology
- Vol. 79 (3), 223-226
- https://doi.org/10.4049/jimmunol.79.3.223
Abstract
The use of both I131 labelled antigens and I131 labelled antibodies allowed calculations of the antigen-antibody ratios of the soluble complexes precipitated by complement in the different regions of antigen excess. The antigen-antibody molecular ratios of the “limiting” complexes, precipitated in extreme antigen excess, afforded a calculation of the valence of the antibody. A valence of approximately 2 was obtained for rabbit anti-BSA and anti-BGG. These values were supported by determinations made with soluble complexes precipitated with chicken anti-RGG.Keywords
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