A comparison of some immunological methods for the differentiation of strains of foot-and-mouth disease virus
- 1 April 1975
- journal article
- research article
- Published by Cambridge University Press (CUP) in Epidemiology and Infection
- Vol. 74 (2), 215-225
- https://doi.org/10.1017/s002217240002427x
Abstract
SUMMARY: Two FMDV strains which had been previously differentiated by complement-fixation were compared by guinea-pig protection test, kinetic neutralization and micro-neutralization tests. It was found that these tests, which have not been previously applied by the methods described, were all capable of FMDV strain differentiation. Similar differences were found by all methods, which suggests that comparisons made by cross-CF, cross-neutralization or cross-protection involve measurement of the same antigen/antibody interactions.Keywords
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