MOST SURGEONS do not encounter more than a single case of adenocarcinoma of the appendix in a lifetime; nevertheless, when a case is confronted, all surgeons should know what constitutes adequate treatment for this malignant disease. Report of a Case A 75-year-old white man entered St. Joseph Hospital on June 12, 1959, with a 12-hour history of midabdominal pain which had later moved to the right lower quadrant. Examination revealed well-localized tenderness over McBurney's point associated with rebound tenderness in the same area. Acute appendicitis was diagnosed, and a grossly inflamed appendix was removed. Gross pathological examination of the specimen revealed that 2.5 cm. of the distal portion was enlarged to a diameter of 1.6 cm.; section of this area showed a soft, gray, bulging tumor which completely obliterated the lumen. Microscopic examination revealed the mucosa to be partially replaced by a neoplasm composed of atypical glands compactly arranged within