Kasugamycin Resistance: 30 S Ribosomal Mutation with an Unusual Location on the Escherichia coli Chromosome
- 2 January 1970
- journal article
- other
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 167 (3914), 56-58
- https://doi.org/10.1126/science.167.3914.56
Abstract
A mutation in Escherichia coli to resistance to the aminoglycoside antibiotic kasugamycin alters the 30S ribosomal subunit. Though all other known 30S ribosomal mutations are located in a cluster in the streptomycin region, kasugamycin resistance is located at a distance from this region, near the leucine region.Keywords
This publication has 9 references indexed in Scilit:
- Antibiotic inhibitors of the bacterial ribosomeMicrobiology and Molecular Biology Reviews, 1968
- Ribosomes from Escherichia coli merodiploids heterozygous for resistance to streptomycin and to spectinomycinJournal of Molecular Biology, 1968
- ADENYL YLSTREPTOMYCIN, A PRIDUCT OF STREPTOMYCIN INACTIVATED BY E.COLI CARRYING R FACTORThe Journal of Antibiotics, 1968
- INHIBITION BY KASUGAMYGIN OF PROTEIN SYNTHESIS IN PIRICULARIA ORYZAEThe Journal of Antibiotics, 1968
- Revised linkage map of Escherichia coliMicrobiology and Molecular Biology Reviews, 1967
- Effect of spectinomycin on polypeptide synthesis in extracts of Escherichia coliJournal of Molecular Biology, 1967
- Mechanism of Kasugamycin Action on Polypeptide SynthesisThe Journal of Biochemistry, 1966
- Optimal conditions for mutagenesis by N-methyl-N′-nitro-N-nitrosoguanidine in escherichia coli K12Biochemical and Biophysical Research Communications, 1965
- STUDIES ON THE RIBOSOMES OF STREPTOMYCIN-SENSITIVE AND RESISTANT STRAINS OF ESCHERICHIA COLIProceedings of the National Academy of Sciences, 1964