R factor-mediated polarized chromosomal transfer in Escherichia coli C

Abstract

Five transferable drug resistance factors (R factors) capable of chromosomal transfer in E. coli C were investigated with respect to the direction and origin of chromosome transfer. They constituted 2 groups, both with a clockwise direction of transfer. One group has its origin of transfer between arg and pro; the other group has, its origin of transfer between try and man. With 1 R factor in particular, the rapid increase in the production of recombinants was followed by a decrease in numbers as mating was prolonged.