Bilateral Carcinoma of the Breast Epidemiology and histopathology

Abstract

A history of previous carcinoma in the contralateral breast was found in 66 of 1351 women (5%) consecutively diagnosed as having breast carcinoma. The mean time interval between the diagnosis of 1st and 2nd tumor was 10.0 yr (range 0-37 yr); 63 of the tumors were metachronous. No significant differences were found between the 1st and the 2nd carcinoma with respect to the Ackerman malignancy grading or the frequency of axillary node involvement. High risk groups for bilateral disease could not be defined on the basis of information about familial occurrence parity, age at 1st birth or malignancy grade.