ESTRADIOL 17 AND CELL MULTIPLICATION - DESCRIPTION OF AN INDIRECT EFFECT
- 1 January 1982
- journal article
- research article
- Vol. 294 (1), 31-34
Abstract
Castrated quails were perfused for 24 h with estradiol-17.beta. (E2: 2 ng/mn) through either the jugular vein or the portal vein. The parameters compared included: plasma E2 levels, changes in oviduct weight, DNA and soluble protein content, estrogen receptor concentration in nuclear preparations of oviducts and progesterone receptor concentration concentration in the cytosol of oviducts. Evidently, E2 affects the proliferation of cells by an indirect pathway that involve a message generated in the liver. The control of the synthesis of cell-type specific protein required the direct action of E2 at the level of the oviduct cells.This publication has 9 references indexed in Scilit:
- Estrogen Regulation of Follicle-Stimulating Hormone Productionin Vitro:Species Variation*Endocrinology, 1981
- Age-Dependent Participation of the Adenohypophysis and Adrenal Cortex in the Estrogenic Response of the Quail OviductEndocrinology, 1980
- Transcriptional regulation of the ovalbumin and conalbumin genes by steroid hormones in chick oviduct.Journal of Biological Chemistry, 1979
- The Effect of Hypophysectomy on the Quail's Oviduct Response to Low and High Doses of Estradiol Benzoate*Endocrinology, 1978
- The induction of ovalbumin and conalbumin mRNA by estrogen and progesterone in chick oviduct explant culturesCell, 1978
- The Effect of Hypophysectomy on the Uterine Response to EstradiolEndocrinology, 1977
- Synthesis of very low density lipoproteins in the cockerel. Effects of estrogen.JCI Insight, 1976
- Effects of sex hormones on the level of the messenger RNA for the rat hepatic protein alpha 2u globulin.Journal of Biological Chemistry, 1976
- PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENTJournal of Biological Chemistry, 1951