Equilibrium Binding in Immunosensors
- 1 February 1986
- journal article
- Published by Institute of Electrical and Electronics Engineers (IEEE) in IEEE Transactions on Biomedical Engineering
- Vol. BME-33 (2), 133-138
- https://doi.org/10.1109/tbme.1986.325887
Abstract
An in vitro solid-phase immunoassay system was studied in order to characterize immunosensor binding reactions. Several variables were explored, including the spacing of immobilized antibodies and the size and valence of analyte analogs. Under appropriate conditions, binding enhancement was observed, suggesting that the chemistry of the system can be experimentally controlled in order to meet specified criteria for sensitivity and other characteristics of the biosensor.Keywords
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