Abstract
1. The toxicity series for the chief cations in sea water for Ligia baudiniana changes with the concentration of the single salts. In a weak solution Na is the most toxic but in 5/8 M concentrations it is the least toxic ion. 2. It is suggested that this is due to permeability effects in hypotonic solutions. 3. Na and Ca gave the most favorable binary mixture. 4. When kept in air with access to solutions of single salts Ligia shows the same toxicity series with respect to K, Na, and Ca as when immersed in isosmotic solutions.