Unusual clinical courses of adult T-cell leukemia in siblings
Open Access
- 1 July 1984
Abstract
Two siblings who developed adult T‐cell leukemia (ATL) with unusual clinical courses are presented. The brother showed spontaneous remissions at the beginning stage of the disease of 6 years' duration, and the sister remains free of complaints for 6 years without chemotherapy. The patients and 2 of 12 healthy members of their family examined had serum antibodies against ATL‐associated antigens (ATLA). The expression of ATLA was observed in the cultured lymphocytes from the patients and one of the family members.This publication has 10 references indexed in Scilit:
- The virus of Japanese adult T-cell leukaemia is a member of the human T-cell leukaemia virus groupNature, 1982
- Natural antibodies to the structural core protein (p24) of the human T-cell leukemia (lymphoma) retrovirus found in sera of leukemia patients in JapanProceedings of the National Academy of Sciences, 1982
- Adult T-cell leukemia: antigen in an ATL cell line and detection of antibodies to the antigen in human sera.Proceedings of the National Academy of Sciences, 1981
- Surface phenotype of Japanese adult T-cell leukemia cells characterized by monoclonal antibodiesBlood, 1981
- A monoclonal antibody (anti-Tac) reactive with activated and functionally mature human T cells. II. Expression of Tac antigen on activated cytotoxic killer T cells, suppressor cells, and on one of two types of helper T cells.The Journal of Immunology, 1981
- SURFACE PHENOTYPE OF JAPANESE ADULT T-CELL LEUKEMIA-CELLS CHARACTERIZED BY MONOCLONAL-ANTIBODIES1981
- Detection and isolation of type C retrovirus particles from fresh and cultured lymphocytes of a patient with cutaneous T-cell lymphomaProceedings of the National Academy of Sciences, 1980
- Age-Related Changes in Suppressor Functions of Human T CellsThe Journal of Immunology, 1979
- Adult T-cell leukemia: clinical and hematologic features of 16 casesBlood, 1977
- Functional analysis of two human T-cell subpopulations: help and suppression of B-cell responses by T cells bearing receptors for IgM or IgG.The Journal of Experimental Medicine, 1977