Antibody Response to Heterologous Protein in Rabbits of Varying Maturity.

Abstract

Neonatal rabbits respond to a single injection of BSA in a dose of 200 mg/kilo body weight with antibody production when given at 28 days of age or older and are unresponsive when this weight-adjusted amount of BSA is given at 8 days of age or younger. At 14 and 21 days of age the response is varied and the majority injected at 14 days of age are unresponsive while most formed antibody when injected at 21 days of age.