A FORTRAN program for the calculation and analysis of two-locus linkage disequilibrium coefficients
- 1 August 1985
- journal article
- research article
- Published by Springer Nature in Theoretical and Applied Genetics
- Vol. 70 (5), 491-496
- https://doi.org/10.1007/bf00305981
Abstract
A FORTRAN program was written that calculates composite linkage disequilibrium coefficients from genotypic data. Chi-square tests determine whether coefficients calculated for allele and locus pairs are significantly greater than zero. A subroutine is provided that partitions the variance in linkage disequilibrium into within- and between-subpopulation components. Output obtained from analysis of allozyme data collected from natural subpopulations of the house fly (Musca domestica L.) are included to illustrate features of the program.Keywords
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