Nucleotide Torsional Flexibility in Solution and the Use of the Lanthanides as Nuclear‐Magnetic‐Resonance Conformational Probes
- 1 April 1978
- journal article
- research article
- Published by Wiley in European Journal of Biochemistry
- Vol. 85 (2), 463-470
- https://doi.org/10.1111/j.1432-1033.1978.tb12261.x
Abstract
The single family of conformations of 5''-AMP in aqueous solution previously obtained using the lanthanide ions as NMR probes is shown to disagree with the conformational data available from independent NMR methods, such as coupling constants and nuclear Overhauser enhancement analysis. The original lanthanide experimental data is reinterpreted assuming the contribution of different conformers to the observed magnetic perturbations. The average conformation obtained for 5''-AMP agrees quite satisfactorily with the other independent conformational information.This publication has 23 references indexed in Scilit:
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