A mathematical model of the kinetics and tissue distribution of 2-fluoro-β-alanine, the major catabolite of 5-fluorouracil
- 25 April 1993
- journal article
- Published by Elsevier in Biochemical Pharmacology
- Vol. 45 (10), 2063-2069
- https://doi.org/10.1016/0006-2952(93)90017-q
Abstract
No abstract availableKeywords
This publication has 14 references indexed in Scilit:
- Disposition and metabolism of 2-fluoro-β-alanine conjugates of bile acids following secretion into bileBiochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, 1991
- 2-Fluoro-β-alanine, a previously unrecognized substrate for bile acid coenzyme A:Amino acid:N-acyltransferase from human liverBiochemical Pharmacology, 1990
- Biological properties of the 2-fluoro-β-alanine conjugates of cholic acid and chenodeoxycholic acid in the isolated perfused rat liverBiochimica et Biophysica Acta (BBA) - Molecular Cell Research, 1990
- Experimental neurotoxicity of 5-fluorouracil and its derivatives is due to poisoning by the monofluorinated organic metabolites, monofluoroacetic acid and ?-fluoro?-alanineActa Neuropathologica, 1990
- Metabolism of pyrimidine analogues and their nucleosidesPharmacology & Therapeutics, 1990
- Clinical Pharmacology of 5-FluorouracilClinical Pharmacokinetics, 1989
- Fluorouracil: biochemistry and pharmacology.Journal of Clinical Oncology, 1988
- Neuropathologic study on chronic neurotoxicity of 5-fluorouracil and its masked compounds in dogsActa Neuropathologica, 1984
- Cardiotoxic effects of 5-fluorouracil in the guinea pig.The Japanese Journal of Pharmacology, 1980
- Biochemical Basis for Fluorouracil NeurotoxicityArchives of Neurology, 1970