Prevention by Calciphylaxis of the Progeria-Like Syndrome Induced by Chronic Dihydrotachysterol Overdosage

Abstract

Experiments on rats indicate that the syndrome of chronic intoxication with dihydrotachysterol (DHT)[long dash]including mortality, the Monckeberg-type of arteriosclerosis, the loss of weight, and the loss of skin elasticity[long dash]can be prevented by the repeated intraperitoneal administration of Fe(OH)3 with dextran (Fe-Dex).