An Improved Procedure for the Regioselective Acetylation of Monosaccharide Derivatives by Pancreatin-Catalyzed Transesterification in Organic Solvents

Abstract

A series of pyranosidic and furanosidic monosaccharide derivatives were monoacetylated in the 6-position with high regioselectivity and good to excellent yields by the pancreatin-catalyzed transesterification with vinyl acetate in the solvent system tetrahydrofuran/triethylamine.