Integrative Genetic Element That Reverses the Usual Target Gene Orientation
- 1 February 2002
- journal article
- Published by American Society for Microbiology in Journal of Bacteriology
- Vol. 184 (3), 859-60
- https://doi.org/10.1128/jb.184.3.859-860.2002
Abstract
A genetic element integrating site specifically into a prokaryotic gene usually carries a copy of the 3′ portion of that gene that restores the active gene even as the original is disrupted. A cryptic element in Mesorhizobium loti instead carries a copy of the 5′ end of the tRNA gene into which it integrated. This has implications for the evolution of new integrase-site combinations.Keywords
This publication has 9 references indexed in Scilit:
- Integration sites for genetic elements in prokaryotic tRNA and tmRNA genes: sublocation preference of integrase subfamiliesNucleic Acids Research, 2002
- Assembly and activation of site-specific recombination complexesProceedings of the National Academy of Sciences, 2000
- Complete Genome Structure of the Nitrogen-fixing Symbiotic Bacterium Mesorhizobium lotiDNA Research, 2000
- Codon usages in different gene classes of the Escherichia coli genomeMolecular Microbiology, 1998
- Evolution of rhizobia by acquisition of a 500-kb symbiosis island that integrates into a phe-tRNA geneProceedings of the National Academy of Sciences, 1998
- Structure of the P22 att site. Conservation and divergence in the lambda motif of recombinogenic complexes.Journal of Biological Chemistry, 1994
- Chromosomal insertion sites for phages and plasmidsJournal of Bacteriology, 1992
- Site-specific integration of the Haemophilus influenzae bacteriophage HP1. Identification of the points of recombinational strand exchange and the limits of the host attachment site.Journal of Biological Chemistry, 1992
- Transfer RNA genes frequently serve as integration sites for prokaryotic genetic elementsNucleic Acids Research, 1989