Clinical Radioimmunodetection of Cancer with Radioactive Antibodies to Human Chorionic Gonadotropin
- 13 June 1980
- journal article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 208 (4449), 1284-1286
- https://doi.org/10.1126/science.7375942
Abstract
Injection of iodine-131-labeled goat immunoglobulin G antibody to human chorionic gonadotropin (hCG) into patients with hCG-secreting trophoblastic and germinal tumors permitted tumor detection and location by external gamma-ray scintigraphy. Excision of one of the metastatic tumors located by this method indicated a tumor/nontumor ration of 39.29. The method appears to offer a new clinical tool for precisely locating hCG-producing tumors in the body, even when tumor identification by other clinical methods has failed.Keywords
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