Pyloric stenosis in adults: A clinical and radiological study of 100 consecutive patients

Abstract

Major causes were duodenal ulcers and prepyloric carcinoma. In early stages, obstruction is overcome by hyperactivity of the gastric muscle; later, muscle failure occurs, with gastric atony and retention of food. This decompensated stage may involve intracellular K or Mg transfer. Fluid and electrolyte replacement, gastric washout and a strict ulcer diet can cause reversion to a compensated stage, and these measures should be used pre-operatively.