An electrooculographic study of internuclear ophthalmoplegia
- 1 November 1977
- journal article
- research article
- Published by Wiley in Annals of Neurology
- Vol. 2 (5), 385-392
- https://doi.org/10.1002/ana.410020507
Abstract
The eye movements of 25 patients with internuclear ophthalmoplegia were recorded by electrooculography. The velocity of adducting saccades was markedly less than normal. The velocity of abducting sacades was within the normal range, but statistically there was a wider distribution. Recordings were made in 2 patients several months after the onset of internuclear ophthalmoplegia, at which time the adducting eye velocity was greater than the abducting eye velocity. A patient with a unilateral medial fasciculus lesion showed marked overshoot of the abducting eye on contralateral saccades and overshoot of both eyes toward the side of the lesion. Optokinetic and postcaloric nystagmus were recorded, and the slow phase showed increasing velocity exponential waveform for the abducting eye. The recordings also showed decreasing velocity exponential waveform for the abducting eye. Downbeat nystagmus was as common as upbeat nystagmus in our patients. The findings appear to confirm the theoretical analysis of the eye movement disorder in internuclear ophthalmoplegia provided by Pola and Robinson as modified by recent experimental work in primates.Keywords
This publication has 22 references indexed in Scilit:
- THE EARLY DIAGNOSIS OF MULTIPLE SCLEROSIS BY MONOCULAR REGISTRATION OF EVOKED NYSTAGMUSActa Neurologica Scandinavica, 2009
- DISORDERS IN CEREBELLAR OCULAR MOTOR CONTROLBrain, 1976
- Internuclear ophthalmoplegia. An electro-oculographic study of peak angular saccadic velocities.British Journal of Ophthalmology, 1976
- An Explanation of Eye Movements Seen in Internuclear OphthalmoplegiaArchives of Neurology, 1976
- Failure of fixation suppressionNeurology, 1974
- Optokinetic Asymmetry in Internuclear OphthalmoplegiaArchives of Neurology, 1974
- Internuclear Ophthalmoplegia, Typical and AtypicalArchives of Ophthalmology (1950), 1970
- Overshoot and Oscillation in Ocular DysmetriaArchives of Ophthalmology (1950), 1966
- INTERNUCLEAR OPHTHALMOPLEGIA AND PARALYSIS OF HORIZONTAL GAZEActa Ophthalmologica, 1965
- The medial longitudinal fasciculus and disturbances of conjugate horizontal eye movements in the monkeyJournal of Comparative Neurology, 1965