Magnesium Bromide-Promoted E⁄Z-Isomerization of Carbonyl-Conjugated Nitrones and Highly Stereo- and Regioselective Cycloadditions to Allylic Alcohol Dipolarophiles
- 1 January 1995
- journal article
- Published by Oxford University Press (OUP) in Chemistry Letters
- Vol. 24 (1), 49-50
- https://doi.org/10.1246/cl.1995.49
Abstract
A Lewis acid promotes the E- to Z-isomerization of carbonyl-conjugated nitrones. The MgBr2•Et2O-catalyzed cycloadditions to allylic alcohols lead to the exclusive formation of the exo-stereoisomers of isoxazolidine-5-methanols. Participation of the Z-nitrone/MgBr2 complexes is suggested.This publication has 8 references indexed in Scilit:
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