Cerebrosidspeicherung bei Morbus Gaucher. III. Mitteilung.

Abstract

From the spleen and liver of a 5 mos. old child with a lipid-celled splenohepatomegaly, doubtfully diagnosed as either a Gaucher''s disease or Niemann-Pick''s syndrome, the authors isolated increased amounts of the cerebroside kerasin, which they believe is characteristic of Gaucher''s disease. Increased deposits of phosphatids, characteristic of Niemann-Pick''s syndrome, were not found. The methods of extraction, isolation, and identification of these substances are given in detail.