Prediction of the Outcome of Rhesus Haemolytic Disease of the Newborn: Additional Information Using an ADCC Assay
- 1 May 1984
- journal article
- research article
- Published by Wiley in Vox Sanguinis
- Vol. 46 (5), 323-329
- https://doi.org/10.1111/j.1423-0410.1984.tb00093.x
Abstract
An in vitro test system is described which measures the ability of anti-D sera to lyse Rh(D)-positive red cells. This test was applied to anti-D sera from 11 cases of HDN [rhesus hemolytic disease] and tested blind. The ADCC (antibody-dependent cell-mediated cytotoxity) assay apparently can correctly identify those cases where there is a satisfactory clinical outcome despite a high level of anti-D suggesting otherwise. Amniocentesis might therefore be avoided in this group.This publication has 10 references indexed in Scilit:
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