Seroconversion from Hepatitis B e antigen to Anti-HBe in Acute Hepatitis B Virus Infection
- 23 February 1978
- journal article
- research article
- Published by Massachusetts Medical Society in New England Journal of Medicine
- Vol. 298 (8), 439-441
- https://doi.org/10.1056/nejm197802232980807
Abstract
SINCE the description of hepatitis B e antigen (HBeAg) and corresponding antibody to the antigen in 1972,1 these entities have attracted attention because of their apparent clinical implications. The presence of HBeAg in the serum of patients with acute Type B hepatitis has been said to indicate ongoing liver damage and a poor prognosis.2 , 3 However, the clinical implications of HBeAg cannot be evaluated without more information about the appearance and disappearance of the antigen in the natural course of acute hepatitis B virus infection.The study of the temporal course of HBeAg and antibody to it in the serum of . . .This publication has 11 references indexed in Scilit:
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- DECREASING FREQUENCY OF e ANTIGEN WITH AGE IN SERUM OF SYMPTOM-FREE CARRIERS OF HEPATITIS B ANTIGENThe Lancet, 1976
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- e antigen in acute hepatitis B.BMJ, 1976
- INCIDENCE AND CLINICAL SIGNIFICANCE OF e ANTIGEN AND ANTIBODY IN ACUTE AND CHRONIC LIVER DISEASEThe Lancet, 1975
- INCIDENCE AND MEANING OF THE " e " DETERMINANT AMONG HEPATITIS-B-ANTIGEN POSITIVE PATIENTS WITH ACUTE AND CHRONIC LIVER DISEASES: Report from the Copenhagen Hepatitis Acuta ProgrammeThe Lancet, 1974