Primary structure and functional expression from complementary DNA of the rod photoreceptor cyclic GMP-gated channel
- 1 December 1989
- journal article
- Published by Springer Nature in Nature
- Vol. 342 (6251), 762-766
- https://doi.org/10.1038/342762a0
Abstract
The complete amino-acid sequence of the cyclic GMP-gated channel from bovine retinal rod photo-receptors, deduced by cloning and sequencing its complementary DNA, shows that the protein contains several putative transmembrane segments, followed by a region that is similar to the cyclic GMP-binding domains of cyclic GMP-dependent protein kinase. Expression of the complementary DNA produces cyclic GMP-gated channel activity in Xenopus oocytes.Keywords
This publication has 44 references indexed in Scilit:
- Three-dimensional reconstruction of the ribosome from Escherichia coliBiophysical Journal, 1989
- Cyclic GMP-Activated Conductance of Retinal Photoreceptor CellsAnnual Review of Neuroscience, 1989
- Electrical and Biochemical Properties of the cGMP-gated Cation Channel from Rod PhotoreceptorsPublished by Cold Spring Harbor Laboratory ,1988
- Identification, purification, and functional reconstitution of the cyclic GMP-dependent channel from rod photoreceptors.Proceedings of the National Academy of Sciences, 1987
- Solubilization and functional reconstitution of the cGMP-dependent cation channel from bovine rod outer segments.Journal of Biological Chemistry, 1986
- Cyclic GMP-sensitive conductance of retinal rods consists of aqueous poresNature, 1986
- Single cyclic GMP-activated channel activity in excised patches of rod outer segment membraneNature, 1986
- Cyclic GMP Cascade of VisionAnnual Review of Neuroscience, 1986
- Control of the light-regulated current in rod photoreceptors by cyclic GMP, calcium, and l-cis-diltiazem.Proceedings of the National Academy of Sciences, 1986
- Induction by cyclic GMP of cationic conductance in plasma membrane of retinal rod outer segmentNature, 1985