New Model of Oropharyngeal Candidiasis in Mice
Open Access
- 1 November 2001
- journal article
- research article
- Published by American Society for Microbiology in Antimicrobial Agents and Chemotherapy
- Vol. 45 (11), 3195-3197
- https://doi.org/10.1128/aac.45.11.3195-3197.2001
Abstract
We established a straightforward murine model of oropharyngeal candidiasis. Mice were immunosuppressed with cortisone acetate, anesthetized, and then inoculated by placing cotton wool balls saturated with Candida albicans sublingually for 2 h. A prolonged, reproducible infection was induced. This model may be useful for antifungal screening or pathogenesis studies.Keywords
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