PhosphinooxazolinesA New Class of Versatile, Modular P,N-Ligands for Asymmetric Catalysis
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- 5 May 2000
- journal article
- review article
- Published by American Chemical Society (ACS) in Accounts of Chemical Research
- Vol. 33 (6), 336-345
- https://doi.org/10.1021/ar9900865
Abstract
Chiral phosphinooxazolines (PHOX ligands), which coordinate to a metal center with a N- and a P-atom, allow effective enantiocontrol in a variety of metal-catalyzed reactions. They are readily synthesized, and because of their modular structure, the steric and electronic properties can be tailored for a specific application by variation of the oxazoline ring, the backbone, and the phosphine moiety.Keywords
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