In Vitro Activity of Antimicrobial Agents on Legionnaires Disease Bacterium
Open Access
- 1 January 1978
- journal article
- research article
- Published by American Society for Microbiology in Antimicrobial Agents and Chemotherapy
- Vol. 13 (1), 78-80
- https://doi.org/10.1128/aac.13.1.78
Abstract
Six isolates of Legionnaires disease bacteria were tested for their susceptibility to 22 antimicrobial agents. The most active agent was rifampin (minimal inhibitory concentration, ≤0.01 μg/ml). On the basis of minimal inhibitory concentration breakpoints that have been used to categorize susceptibility for most of these drugs, the organisms were susceptible to rifampin, cefoxitin, erythromycin, the aminoglycosides, minocycline and doxycycline, chloramphenicol, ampicillin, penicillin G, carbenicillin, colistin, and sulfamethoxazole-trimethoprim (19:1 ratio); sensitive to intermediate in susceptibility to tetracycline, methicillin, cefamandole, cephalothin, and clindamycin; and resistant to vancomycin. More clinical data must be obtained before an optimal therapeutic regimen can be recommended.This publication has 2 references indexed in Scilit:
- Activity of Minocycline Against Acinetobacter calcoaceticus Var. anitratus (Syn. Herellea vaginicola ) and Serratia MarcescensAntimicrobial Agents and Chemotherapy, 1975
- Laboratory Evaluation of a Rapid, Automated Susceptibility Testing System: Report of a Collaborative StudyAntimicrobial Agents and Chemotherapy, 1975