Insulin receptors on monocytes of young healthy persons correlated with glucose tolerance and insulin sensitivity
- 1 March 1978
- journal article
- research article
- Published by Springer Nature in Diabetologia
- Vol. 14 (3), 159-163
- https://doi.org/10.1007/bf00429775
Abstract
We have studied in normal man the inter-relationships between insulin binding to monocytes, glucose tolerance and insulin sensitivity. In 25 young healthy persons we found a significant positive correlation between insulin binding and glucose disappearance rate both after glucose (R = 0.68, p<0.01) and insulin (R = 0.49, p<0.02) given intravenously.This publication has 23 references indexed in Scilit:
- The monocyte as a model for the study of insulin receptors in manDiabetologia, 1977
- Correlation between insulin receptor binding in isolated fat cells and insulin sensitivity in obese human subjects.JCI Insight, 1976
- Fluctuations in the affinity and concentration of insulin receptors on circulating monocytes of obese patients: effects of starvation, refeeding, and dieting.JCI Insight, 1976
- Decreased insulin binding to adipocytes and circulating monocytes from obese subjects.JCI Insight, 1976
- The effects of spontaneous obesity on insulin binding, glucose transport, and glucose oxidation of isolated rat adipocytes.JCI Insight, 1976
- The biological activity and the binding affinity of modified insulins determined on isolated rat fat cellsDiabetologia, 1974
- The significance and interpretation of mildly abnormal oral glucose toleranceDiabetologia, 1971
- Monoiodoinsulin: Demonstration of its biological activity and binding to fat cells and liver membranesBiochemical and Biophysical Research Communications, 1971
- The Glomerular Permeability Determined by Dextran Clearance Using Sephadex Gel FiltrationScandinavian Journal of Clinical and Laboratory Investigation, 1968
- Intravenous Glucose Tolerance as a Tool in Definition and Diagnosis of Diabetes MellitusBMJ, 1962