A Clinical Pilot Study On Preformed Autologous Ossicles. I
- 31 December 1977
- journal article
- research article
- Published by Taylor & Francis in Acta Oto-Laryngologica
- Vol. 85 (1-6), 33-39
- https://doi.org/10.3109/00016487809121420
Abstract
The study is part of a project aimed at obtaining an autologous, preformed transplant for reconstruction of a defect ossicular chain. In animal experiments we found that bone could be produced in a titanium mould placed in the tibia of the rabbit and dog. To find out whether this observation was applicable in man, 5 patients with ossicular defects were selected. A titanium mould containing two chambers was placed in the proximal tibial metaphysis for 6 months. When the moulds were extracted bone was found in 7 of the 10 chambers. In 2 of these the bone was stable and suitable for ossiculo-plasty. On histological examination the same picture as in the animal experiments was found, an outer layer of cortical bone surrounding a system of spongy bone with marrow and haematopoietic cells. Microradiological examination verified the presence of mineralized bone tissue.This publication has 15 references indexed in Scilit:
- Preformed Autologous OssiclesExperimental StudiesActa Oto-Laryngologica, 1975
- The use of proplasttm in otologic surgery.The Laryngoscope, 1974
- Total Middle Ear ReconstructionActa Oto-Laryngologica, 1973
- Intra-Osseous Anchorage of Dental Prostheses:I. Experimental StudiesScandinavian Journal of Plastic and Reconstructive Surgery, 1969
- Tympanic Membrane Grafting With Temporalis FasciaJAMA Otolaryngology–Head & Neck Surgery, 1967
- Present Status of Vein Graft TympanoplastyJAMA Otolaryngology–Head & Neck Surgery, 1965
- Ossicular Repositioning and Ossicular Prostheses in TympanoplastyJAMA Otolaryngology–Head & Neck Surgery, 1960
- MyringoplastyJAMA Otolaryngology–Head & Neck Surgery, 1960
- Prognose Und Resultat Der TympanoplastikActa Oto-Laryngologica, 1955
- Prothesis Treatment and its Healing effect on Central Perforations of the Tympanic MembraneActa Oto-Laryngologica, 1951