Apoptosis‐inducing factor (AIF): a ubiquitous mitochondrial oxidoreductase involved in apoptosis
Open Access
- 3 July 2000
- journal article
- review article
- Published by Wiley in FEBS Letters
- Vol. 476 (3), 118-123
- https://doi.org/10.1016/s0014-5793(00)01731-2
Abstract
Apoptosis‐inducing factor (AIF) is encoded by one single gene located on the X chromosome. AIF is ubiquitously expressed, both in normal tissues and in a variety of cancer cell lines. The AIF precurs...Keywords
This publication has 22 references indexed in Scilit:
- Mass spectrometric identification of proteins released from mitochondria undergoing permeability transitionCell Death & Differentiation, 2000
- Biochemical Pathways of Caspase Activation During ApoptosisAnnual Review of Cell and Developmental Biology, 1999
- Apoptosis inducing factor (AIF): a phylogenetically old, caspase-independent effector of cell deathCell Death & Differentiation, 1999
- Presence of a pre-apoptotic complex of pro-caspase-3, Hsp60 and Hsp10 in the mitochondrial fraction of Jurkat cellsThe EMBO Journal, 1999
- The central executioners of apoptosis: caspases or mitochondria?Trends in Cell Biology, 1998
- Mitochondria and ApoptosisScience, 1998
- A Cytofluorometric Assay of Nuclear Apoptosis Induced in a Cell-Free System: Application to Ceramide-Induced ApoptosisExperimental Cell Research, 1997
- Bcl-2 inhibits the mitochondrial release of an apoptogenic protease.The Journal of Experimental Medicine, 1996
- Induction of Apoptotic Program in Cell-Free Extracts: Requirement for dATP and Cytochrome cCell, 1996
- Mitochondrial control of nuclear apoptosis.The Journal of Experimental Medicine, 1996