Patients (14) with tremor and acquired peripheral neuropathies of different origin were studied. Minimal weakness was the only clinical finding common to all patients. Sensory changes, etiology and course of the neuropathy varied. No unique pattern of peripheral nerve histopathology could be demonstrated. Slowing of conduction velocity of Ia fibers was found, but the role played by impairment of sensory inputs remains unclear. Tremor associated with peripheral neuropathy seems to be due to enhancement of physiologic tremor by minimal weakness.