Abstract
The JH virus was found in association with an upper-respiratory outbreak in children. Children given a vaccine prepared from inactivated JH virus showed an attack rate about eight times lower than that of the children receiving the placebo injections. No untoward reactions were observed in 401 individuals receiving the vaccine, which was prepared from inactivated JH virus grown in monkey kidney epithelial tissue. It is concluded that the JH virus is the cause of a coldlike illness in humans and that an inactivated vaccine can be prepared from this virus which protects against the overt illness due to the JH virus.