Repair and Replication of X-irradiated HeLa Cell DNA
- 1 January 1971
- journal article
- research article
- Published by Taylor & Francis in International Journal of Radiation Biology and Related Studies in Physics, Chemistry and Medicine
- Vol. 19 (4), 339-348
- https://doi.org/10.1080/09553007114550461
Abstract
Non-semi-conservative DNA synthesis assayed by CsCl density gradient analysis has been detected in synchronous G1-phase HeLa cells irradiated with less than 1000 rads x-rays. The dose response is linearly proportional up to 5000 rads. A time course study shows the ‘repair’ is completed during 1–2 hours after irradiation. 80 per cent of the ‘repaired’ DNA is subsequently replicated.Keywords
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