Iodine-125, a tracer in cell biology: physical properties and biological aspects
- 1 July 1970
- journal article
- Published by IOP Publishing in Physics in Medicine & Biology
- Vol. 15 (3), 447-456
- https://doi.org/10.1088/0031-9155/15/3/005
Abstract
Some essential physical properties of the transmutation of iodine-125 are discussed and the range of its electrons calculated. Its suitability for autoradiographs is compared with that of tritium. The dose distribution around a point source and the dose absorbed by a cell nucleus labelled with 125I and 3H are calculated. It is suggested that the biological toxicity of iodine-125 is not only due to energy deposition of its radiation but also to molecular fragmentation caused by charge transfer in consequence of the Auger effect.Keywords
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