Antiprotozoal activity of the constituents of Teloxys graveolens
- 7 August 2003
- journal article
- research article
- Published by Wiley in Phytotherapy Research
- Vol. 17 (7), 731-732
- https://doi.org/10.1002/ptr.1192
Abstract
Antiprotozoal activity‐guided fractionation of a methanol extract of the aerial parts of Teloxys graveolens led to the isolation of one coumarinic acid derivative, melilotoside, and five flavonoids, pinocembrine, pinostrobin, chrysin, narcissin and rutin. Among them, melilotoside exhibited the most potent activity toward Entamoeba histolytica and Giardia lamblia (IC50 12.5 and 16.8 µg/mL, respectively). Narcissin showed selectivity against E. histolytlica (IC50 17.2 µg/mL). The results support data for the traditional use of T. graveolens in some gastrointestinal diseases. Copyright © 2003 John Wiley & Sons, Ltd.Keywords
Funding Information
- National Council of Science and Technology (CONACyT) (28328N)
This publication has 9 references indexed in Scilit:
- Antiprotozoal Activity of the Constituents of Conyza filaginoidesJournal of Natural Products, 2001
- Antimicrobial activity of flavonoids in medicinal plants from Tafı́ del Valle (Tucumán, Argentina)Journal of Ethnopharmacology, 2000
- Geranins A and B, New Antiprotozoal A-Type Proanthocyanidins from Geranium niveumJournal of Natural Products, 1999
- Antiamoebic and Antigiardial Activity of Plant Flavonoids**Planta Medica, 1999
- The effects of chrysin and pinostrobin, two flavonoids isolated from Teloxys graveolens leaves, on isolated guinea-pig ileumPhytomedicine, 1998
- The Flavonoid Constituents of TwoPolypodiumSpecies (Calaguala) and their Effect on the Elastase Release in Human NeutrophilsPlanta Medica, 1997
- Screening for antimicrobial activity of crude drug extracts and pure natural products from Mexican medicinal plantsJournal of Ethnopharmacology, 1992
- Pinocembrine: A bioactive flavanone from Teloxys graveolensJournal of Ethnopharmacology, 1991
- Flavonoids and terpenoids of Chenopodium graveolensPhytochemistry, 1986