Separation of pineal extracts by gelfiltration
- 1 March 1976
- journal article
- research article
- Published by Springer Nature in Journal of Neural Transmission
- Vol. 38 (1), 31-41
- https://doi.org/10.1007/bf01254138
Abstract
Aqueous extracts of sheep pineal bodies were separated on Sephadex G-25. A low molecular Sephadex G-25 fraction F 4 was filtrated on Sephadex G-10. Several distinct peaks could be detected showing excitation and fluorescence maxima resembling those of indoles. A thinlayer chromatography study revealed that one Sephadex G-10 peak contained a spot identical with that of synthetic 5-methoxytryptophol, another a spot with the same Rf-values in different solvents as synthetic 5-hydroxytryptophol, while from a third peak a substance was isolated identical with synthetic melatonin. Mass spectra of the isolated compounds were recorded. These results are compared with those of previous isolation studies.This publication has 11 references indexed in Scilit:
- Localization of a sheep pineal antigonadotropinAnalytical Biochemistry, 1973
- The inhibitory effect of 5-methoxytryptophol on ovarian weight, follicular growth and egg production of adult white leghorn hens (Gallus domesticus L.)Journal of Neural Transmission, 1973
- The stimulatory effects of several concentrations of 5-methoxytryptophol on testicular growth in the white leghorn (Gallus domesticus L.)Journal of Neural Transmission, 1973
- Separation of pineal extracts on sephadex G-10Journal of Neural Transmission, 1972
- Separation of pineal extracts on sephadex G-10Analytical Biochemistry, 1972
- Age-dependent effects of 5-methoxytryptophol and melatonin on testes and comb growth of the white leghorn (Gallus Domesticus L.)Journal of Neural Transmission, 1972
- Separation of pineal extracts on sephadex G-10Journal of Neural Transmission, 1970
- Brain Receptors Sensitive to Indole Compounds: Function in Control of Luteinizing Hormone SecretionScience, 1968
- Indole Compounds: Isolation from Pineal TissueScience, 1965
- 5-Methoxytryptophol: Effect on Estrus and Ovarian WeightScience, 1964