Antigen-Antibody Reactions in Rat Brain Sites Induce Transient Changes in Drinking Behavior
- 15 April 1977
- journal article
- research article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 196 (4287), 328-330
- https://doi.org/10.1126/science.191911
Abstract
The septum or hypothalamus of rat brain was injected through implanted cannulas with antibody against membrane antigens in the rat brain or with antibody against exogenous soluble antigens (such as ovalbumin) followed by the specific antigen. Both immunological systems produced a moderate but highly significant decrease in drinking by thirsty rats. This phenomenon is suggested as an experimental model for behavioral disorders resulting from nondegenerative, immunological processes in the brain.This publication has 39 references indexed in Scilit:
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