Simian Virus 40-Induced T and Tumor Antigens
- 1 November 1969
- journal article
- Published by American Society for Microbiology in Journal of Virology
- Vol. 4 (5), 574-9
- https://doi.org/10.1128/jvi.4.5.574-579.1969
Abstract
Antigen extracts from simian virus 40 (SV40) transplanted hamster tumors were studied by rate-zonal centrifugation. Three species or molecular forms of antigen were demonstrated. The major antigen component corresponded to a molecular weight of 65,000 to 75,000, and two larger species were detectable in smaller quantities. Similar studies were carried out on SV40 virus-induced T antigen from BSC-1 cells. Three antigen components were again detected. Quantitative differences in the expression of "T" and tumor antigen species were reproducibly found.Keywords
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